Description:

Interleukin 12 (IL-12) is an interleukin that plays important roles in the activities of natural killer cells and T lymphocytes, the differentiation of naive T cells into Th1 cells, the growth and function of T cells, the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-a) from T and natural killer (NK) cells, and IL-4 mediated suppression of IFN-γ. It also plays a role in anti-angiogenic activity by increasing production of IFN-?, which in turn increases the production of IP-10. IL-12 is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells in response to antigenic stimulation.

Signosis 是一家专业的生物分析供应商，致力于基于微孔板分析技术的生命科学研究产品的开发、生产和销售。Signosis 成立于2007年，坐落于世界研发中心--美国硅谷的中心地带。公司专注于细胞因子、转录因子、miRNA及疾病标志物等重要调控因子和标志物的研究，基于自有专利技术，开发完成400多种先进而独特的用于发现、筛选和分析的生命科学研究产品。Signosis 产品销售遍布北美、欧洲、亚洲及中东等主要国家和地区，客户涵盖美国国立卫生研究院、哈佛大学、耶鲁大学等著名研究机构以及众多制药公司